TABLE 6.
Calculation of the ratio of nonsynonymous to synonymous mutations in DENV proteins under vehicle and UV-4B treatment conditions
| Protein | Glycosylated | Nonsynonymous/synonymous mutations by treatmenta |
|
|---|---|---|---|
| Vehicle | UV-4B | ||
| M | X | 0.00 | 0.30 |
| NS1 | X | 0.00 | 0.26 |
| NS5 | 0.01 | 0.21 | |
| NS4A | 0.00 | 0.20 | |
| prM | X | 0.00 | 0.14 |
| NS2A | 0.00 | 0.11 | |
| E | X | 0.01 | 0.09 |
| NS3 | 0.00 | 0.02 | |
| NS4B | 0.00 | 0.01 | |
| C | 0.00 | 0.00 | |
| NS2B | 0.00 | 0.00 | |
| 2K peptide | 0.00 | 0.00 | |
| Avg | 0.00 | 0.11 | |
a
The ratio of nonsynonymous to synonymous mutations is derived by dividing the fraction of nonsynonymous mutations over all of the nucleotides in that protein by the same quantity for synonymous mutations.