FIG 5.

MARVpv and EBOVpv were able to bind to heparin and HS. (a) An ELISA (described in Materials and Methods) was used to demonstrate specific binding of MARVpv and EBOVpv to heparin and HS. AIVpv was used here as a specificity control. Error bars represent standard deviations. (b) An ELISA-based competition experiment was used to demonstrate that “cold” heparin and HS can competitively block binding of MARVpv and EBOVpv to the heparin used to coat the plates. Error bars represent standard deviations.