Only high-molecular-weight heparin (HMWH) could block MARVpv infection. Porcine heparin (HMWH, ∼17 to 19 kDa) and heparin hexasaccharide (LMWH, ∼1.5 kDa), at the concentrations indicated, were first mixed with MARVpv and then added to the target cells (A549), and infection by MARVpv was determined 48 h postinfection. Error bars represent standard deviations.