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. 2015 Mar 4;89(10):5362–5370. doi: 10.1128/JVI.03188-14

TABLE 4.

EC50s and EC90s of NS3 inhibitors against H77S.3 virus determined by FFU assay

Inhibitor EC50 (nM)
EC90 (nM)
12 h 24 h 48 h 72 h 12 h 24 h 48 h 72 h
Telaprevir 777 (686–880)a 677 (626–733) 765 (695–843) 738 (566–962) 2,778 (2,085–3,701) 1,389 (1,180–1,635) 1,255 (1,080–1,458) 2,493 (1,333–4,664)
AT23708 218 (200–237) 91 (81–101) 108 (97–121) 123 (98–105) 491 (413–583) 428 (328–558) 364 (285–466) 294 (253–342)
a

The values in parentheses are 95% confidence intervals.