FIG 1.

Curation workflow to filter sequences from strains with multiple sequence records. The goal of the curation workflow was to select single sequence records that likely represent natural isolates. If a strain has multiple identical sequence records available, the sequence that was collected or submitted to GenBank with the earliest date was selected. If a strain has multiple heterogeneous sequence records, then the earliest sequence record that is identical to the majority sequence was selected. If there is no majority sequence, then the sequence record with the lowest passage number was selected.