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. Author manuscript; available in PMC: 2015 May 25.
Published in final edited form as: J Clin Oncol Res. 2014 Apr 5;2(4):1028.

Figure 1.

Figure 1

F10 strongly inhibits the clonogenicity of PC3 cells. (A) Structure of F10. (B) Clonogenic survival assay evaluating clonogenic survival of PC3 cells following 72 h treatment with either F10 or 5-FU at the indicated concentration (nM). No surviving colonies were observed following treatment with F10 at 1 μM (1,000 nM). In contrast, treatment with 5FU at 10 μM (10,000 nM) decreased the percent of colonies surviving relative to control by less than 50%. (C) TS activity in PC3 cells at the indicated times following treatment with F10 (10-8 M) or 5-FU (10-6 M) (* p < 0.05 vs control based on Student's two sided t-test).