Table 1.
miR | Tumor vs. Benigna | Conserved Sitesb | p85α Correlationc |
---|---|---|---|
miR-21 | 1.42 | 2 | −0.09 |
miR-617 | −1.13 | 1 | −0.46 |
miR-525-5p | −0.94 | 1 | −0.45 |
miR-936 | −1.52 | 1 | −0.43 |
miR-488 | −3.97 | 1 | −0.41 |
miR-519 | −0.37 | 1 | −0.40 |
miR-635 | −1.28 | 1 | −0.40 |
miR-486-5p | −0.40 | 1 | −0.38 |
miR-634 | 0.24 | 1 | −0.34 |
miR-127-5p | −0.84 | 1 | −0.26 |
miR-498 | 0.71 | 1 | −0.25 |
miR-656 | 0.96 | 1 | −0.24 |
miR-650 | 0.03 | 1 | −0.24 |
miR-1285 | 0.01 | 1 | −0.22 |
miR-1229 | 1.02 | 1 | −0.21 |
miR-554 | −0.31 | 1 | −0.17 |
miR-548o | 0.45 | 1 | −0.16 |
miR-330-3p | −0.53 | 1 | −0.14 |
miR-455-3p | 0.50 | 1 | −0.14 |
miR-767-5p | −1.40 | 1 | −0.10 |
miR-495 | 0.38 | 1 | −0.06 |
miR-221 | 1.01 | 1 | −0.05 |
miR-15a | 0.23 | 1 | −0.01 |
miR-548g | 0.19 | 1 | −0.01 |
Log-transformed p-value of Student’s T-test comparing expression in PDAC tumor cells vs. normal ductal epithelium based on miR array. A positive (negative) value indicates higher (lower) expression in tumor as compared to normal cells.
Number of predicted binding sites in p85α 3′UTR for each miR.
Correlation coefficient between miR and p85α (mRNA) expression levels in PDAC tumor cells.