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. Author manuscript; available in PMC: 2016 Jun 15.
Published in final edited form as: Neurosci Lett. 2015 Apr 15;597:32–37. doi: 10.1016/j.neulet.2015.04.021

Figure 1. Tau−/− cortical neurons are protected from ΔΨm loss induced by low concentrations of Aβ42.

Figure 1

Representative images from t=0 (left) and t=30 (right) of WT (top) and tau−/− (bottom) primary cortical neurons loaded with ΔΨm indicator, MitoRed, and treated with 0.25µM (A) or 5µM Aβ42 (B). Quantification of full time-lapse experiments (C) and the change from t=0 to t=30 (D). Ablation of tau was confirmed via western blot analysis of cortical lysates from tau−/− and WT mouse brains using a tau polyclonal antibody and β-actin monoclonal antibody (E). *=P<0.05