Table 1.
Summary of significant group differences in behavioral, anatomical, and DKI measures. Data is presented as mean ± standard deviation. MD, AD, and RD are expressed in units of 10−3mm2/s. FA, MK, AK, & RK are dimensionless ratios.
| BEHAVIORAL: | ||||
|---|---|---|---|---|
| measure | PO (n=10) | CPF (n=10) | p | |
| - MWM Escape latency | s | 63.7 ± 10.2 | 73.7 ± 11.0 | 0.050 |
| ANATOMICAL: | ||||
|---|---|---|---|---|
| measure | PO (n=10) | CPF (n=10) | p | |
| - Body weight | g | 496.7 ± 47.4 | 441.7 ± 63.4 | 0.041 |
| - Forebrain volume | mm3 | 2827.4 ± 23.9 | 2690.0 ± 34.0 | 0.005 |
| - Striatal volume | mm3 | 111.5 ± 6.8 | 102.3 ± 5.9 | 0.005 |
| DIFFUSION: | ||||
|---|---|---|---|---|
| measure | PO (n=10) | CPF (n=10) | p | |
| - Corpus Callosum | FA | 0.41 ± 0.02 | 0.39 ± 0.02 | 0.014 |
| MK | 0.77 ± 0.03 | 0.74 ± 0.02 | 0.009 | |
| AK | 0.61 ± 0.02 | 0.60 ± 0.05 | 0.008 | |
| RK | 1.01 ± 0.06 | 0.96 ± 0.04 | 0.023 | |
|
| ||||
| - Striatum | FA | 0.21 ± 0.01 | 0.20 ± 0.01 | 0.006 |
| MD | 0.84 ± 0.01 | 0.86 ± 0.02 | 0.012 | |
| RD | 0.74 ± 0.01 | 0.77 ± 0.01 | 0.002 | |
| RK | 0.78 ± 0.02 | 0.75 ± 0.03 | 0.048 | |
|
| ||||
| - Amygdalae | FA | 0.22 ± 0.02 | 0.20 ± 0.01 | 0.002 |
| MD | 0.91 ± 0.01 | 0.92 ± 0.03 | 0.024 | |
| RD | 0.80 ± 0.02 | 0.83 ± 0.02 | 0.002 | |
|
| ||||
| - Forebrain | RK | 0.86 ± 0.06 | 0.81 ± 0.03 | 0.038 |