Table 1.

Participant characteristics

Variable	Mean	SD	Min	Max
Age (years)	57.58	10.89	40.0	81.0
Educationa	12.86	2.67	6.0	18.0
MMSE scoreb	29.15	0.95	27.0	30.0
Comorbidity scorec	6.74	5.95	0.0	24.0
ASA statusd	2.74	0.44	2.0	3.0
MBMD subscale scorese
Depression	44.03	28.79	10.0	100.0
Pessimism	49.81	24.70	10.0	83.0
Dejected	25.03	32.49	0.0	110.0
Anxiety	54.90	28.70	5.0	95.0
BIS values
Baseline BISf	95.29	4.01	83.40	97.70
BIS at inductiong	89.75	10.06	58.00	97.70
AOC scoreh	547.42	108.63	358.85	748.75

^aEducation in years (N=29)

^bMMSE = Mini-Mental State Exam (N=27; best score is 30 points)

^cCharlson comorbidity index ([32]; score range 0 to 33; maximum comorbidity=33)

^dAmerican Society of Anesthesiologists (ASA) physical status classification system (range 1–6; 1 = healthy to 6 = declared brain death)

^eMillon Behavioral Medicine Diagnostic (MBMD) prevalence subscale scores (note: percentage of participants with a clinically significant (i.e., prevalence scores ≥75) MBMD prevalence scores: anxiety-tension (29.0 %), depression (19.4 %), dejected (12.9 %), future pessimism (9.7 %))

^fBispectral index score

^gBIS at induction = time of administration of the induction dose of propofol

^hArea over the curve (see Fig. 2)