TABLE 3.
Plasma peptide levels in male mice as analyzed by multiplex immunoassay
| Analyte (pg/ml) | WT LFD | MGL−/− LFD | WT HFD | MGL−/− HFD |
| Insulin | 333 ± 103 | 249 ± 21 | 724 ± 196 | 255 ± 56a |
| Glucagon | 47 ± 5 | 69 ± 8a | 45 ± 9 | 43 ± 9 |
| C-peptide | 634 ± 166 | 298 ± 55 | 883 ± 164 | 382 ± 85a |
| PP | 18 ± 3 | 38 ± 10 | 17 ± 4 | 23 ± 6 |
| Leptin (ng/ml) | 12 ± 2 | 4 ± 2a | 27 ± 4 | 18 ± 3 |
| Adiponectin (ng/ml) | 15 ± 1 | 14 ± 1 | 13 ± 1 | 15 ± 1 |
| Resistin (ng/ml) | 14 ± 2 | 10 ± 1a | 25 ± 3 | 14 ± 2a |
| GIP | 161 ± 28 | 126 ± 40 | 145 ± 46 | 102 ± 16 |
| PYY | 105 ± 8 | 103 ± 9 | 112 ± 22 | 79 ± 13 |
| MCP-1 | 87 ± 20 | 44 ± 12 | 103 ± 14 | 89 ± 22 |
| TNFα | 23 ± 7 | 19 ± 2 | 20 ± 5 | 32 ± 3 |
| IL-6 | 48 ± 15 | 44 ± 15 | 85 ± 61 | 52 ± 20 |
Data are expressed as average ± SEM (n = 5–6).
a
P < 0.05 compared with control group of the same diet.