Fig. 9.

Mouse atherosclerotic plaque ox-CE analysis. LDLrKO mice were fed the indicated ADs for 16 weeks before aortas were harvested for ox-CE analysis using normal phase-HPLC-MS/MS. Ion chromatograms of CE (2–4 min elution) and ox-CEs (6–36 min elution) for one aorta from each diet group. Inset presents the raw mass spectrometric data corresponding to CE molecular species labeled with m/z values and their acyl components, denoted by total acyl carbons and double bonds in this qualitative study. No ox-CE species were detectable for any of the four diet groups.