Table 1.
Mean (SD) variable at sample time (h) |
||||||
---|---|---|---|---|---|---|
2 |
24 |
48 |
||||
Group | Basal | Test | Basal | Test | Basal | Test |
Serum creatinine (mg/dL) | ||||||
Sham | 0.44 (0.09) | 0.50 (0.14) | 0.45 (0.11) | 0.58 (0.05) | 0.47 (0.07) | 0.62 (0.09) |
Control | 0.52 (0.12) | 0.81 (0.09)⁎ | 0.45 (0.09) | 2.08 (0.46)⁎ | 0.61 (0.06) | 1.38 (0.14)⁎ |
Ipre | 0.44 (0.09) | 0.85 (0.19)⁎ | 0.46 (0.08) | 1.20 (0.26)⁎† | 0.52 (0.09) | 0.85 (0.11)⁎† |
Ipost | 0.48 (0.08) | 0.69 (0.16)‡ | 0.44 (0.11) | 1.64 (0.45)⁎‡ | 0.50 (0.09) | 1.14 (0.29)⁎‡ |
Serum BUN (mg/dL) | ||||||
Sham | 21.10 (2.02) | 25.80 (1.23) | 19.10 (3.02) | 25.10 (2.80) | 21.10 (2.02) | 20.40 (2.71) |
Control | 21.40 (3.75) | 37.10 (3.14)⁎ | 19.50 (3.02) | 49.80 (3.55)⁎ | 19.00 (2.71) | 42.70 (6.17)⁎ |
Ipre | 18.00 (2.67) | 28.40 (3.13)† | 20.10 (2.73) | 29.00 (3.43)† | 19.60 (3.20) | 26.40 (2.79)† |
Ipost | 20.10 (2.42) | 34.90 (3.98)‡ | 19.70 (3.34) | 48.50 (6.43)⁎‡ | 20.60 (3.75) | 39.30 (5.06)⁎‡ |
CrCl (mL/min) | ||||||
Sham | 1.36 (0.37) | – | 1.33 (0.24) | 1.23 (0.42) | 1.41 (0.21) | 1.31 (0.29) |
Control | 1.56 (0.48) | – | 1.34 (0.28) | 0.11 (0.03)⁎ | 1.36 (0.37) | 0.24 (0.05)⁎ |
Ipre | 1.60 (0.26) | – | 1.34 (0.51) | 0.42 (0.12)† | 1.42 (0.27) | 1.100 (0.26)⁎† |
Ipost | 1.81 (0.49) | – | 1.68 (0.36) | 0.19 (0.01)⁎‡ | 1.76 (0.32) | 0.25 (0.08)⁎‡ |
FENa (%) | ||||||
Sham | 0.25 (0.07) | – | 0.27 (0.04) | 0.41 (0.09) | 0.3 1 (0.06) | 0.35 (0.05) |
Control | 0.28 (0.09) | – | 0.34 (0.06) | 0.97 (0.14)⁎ | 0.35 (0.07) | 0.93 (0.19)⁎ |
Ipre | 0.28 (0.04) | – | 0.35 (0.08) | 0.44 (0.11)† | 0.26 (0.05) | 0.34 (0.05)† |
Ipost | 0.29 (0.07) | – | 0.27 (0.08) | 0.88 (0.69)⁎‡ | 0.25 (0.05) | 0.56 (0.21)⁎,‡† |
One-way anova with posthoc Scheffe’s test.
significant (P = 0.05) from the sham group.
significant (P = 0.05) from the control group.
significant (P = 0.05) from the Ipre group.