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Effect of 3 mM histamine on the GABA-induced current of wt or mutated GABAARs. The bars show the increase of the GABA-induced (typically EC10-30) currents by 3 mM histamine of the GABAAR subunit combination (A) α1β2γ2L and (B) α2β3γ2L. Significant data were marked with ∗p ≤ 0.05 and ∗∗p ≤ 0.01.
