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. 2015 May 26;6:106. doi: 10.3389/fphar.2015.00106

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Copyright © 2015 Thiel, Platt, Wolf, Hatt and Gisselmann.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Histamine action on the GABA-induced currents of GABA_ARs with point mutated β3(V175A). (A) Original trace of the effect of 3 mM histamine on the GABA-induced currents of the GABA_AR α2β3(V175A)γ2L. (B) Bar diagram show the effect of various histamine concentrations up to 10 mM on the GABA-induced currents of the GABA_AR α2β3(V175A)γ2L. Significant data were marked with ^∗∗p ≤ 0.01.