Table 2.
Brain region | Age |
|
---|---|---|
Juvenile | Adult | |
CORTEX∗ | 428.33 ± 70.06 | 238.33 ± 36.86 |
PIA∗ | 635.00 ± 185.00 | 163.33 ± 23.63 |
CORPUS CALLOSUM∗ | 753.33 ± 83.87 | 358.33 ± 54.85 |
HIPPOCAMPUS | 580.00 ± 250.60 | 441.67 ± 68.98 |
OLFACTORY BULB | 255.00 ± 80.47 | 204.00 ± 31.75 |
PERIVASCULAR | 391.67 ± 143.38 | 300.00 ± 141.07 |
RMS∗ | 508.33 ± 30.14 | 261.67 ± 41.93 |
SUB CORTEX | 206.67 ± 58.60 | 71.33 ± 8.08 |
SVZ | 555.00 ± 152.23 | 366.67 ± 56.86 |
DG∗ | 1110.00 ± 235.16 | 596.67 ± 80.83 |
CEREB. GRAN | 456.67 ± 60.28 | 388.33 ± 46.46 |
CEREB. MOLE∗ | 395.00 ± 30.41 | 216.67 ± 28.87 |
CEREB. WM | 433.33 ± 51.32 | 343.33 ± 58.60 |
CEREB. PCL∗ | 403.33 ± 25.17 | 306.67 ± 30.55 |
PONS | 280.00 ± 121.24 | 176.67 ± 20.82 |
BRAIN STEM | 170.00 ± 125.30 | 143.33 ± 30.55 |
3RD VENTRICLE | 211.67 ± 34.03 | 213.33 ± 32.15 |
SVZ, Sub Ventricular Zone; CEREB. GRAN., Granular layer of the Cerebellum; CEREB. MOLE., Molecular layer of Cerebellum; CEREB. WM, Cerebellar White Matter; CEREB. PCL, Purkinje Cell Layer of Cerebellum. Age influences the population of astrocytes in different regions of the brain. In all the brain regions, astrocyte count was higher in juveniles than adults except at the third ventricle. Significant difference in mean counts (∗) between juveniles and adults was found in the CORTEX (t = 4.16, p = 0.01), PIA (t = 4.38, p = 0.01), CORPUS CALLOSUM (t = 6.83, p = 0.01), RMS (t = 8.27, p = 0.01), DG (t = 3.58, p = 0.01), CEREB. MOLE. (t = 7.37, p = 0.01) and CEREB. PCL (t = 4.23, p = 0.01). The highest astrocyte counts in both juvenile and adult was found in DG while the least was found in the BRAIN STEM and SUB CORTEX, respectively.