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. 2015 Mar 15;8(3):3338–3348.

Table 1.

Baseline characteristics of the trials included in the meta-analysis

Author Treatment regimen No. of patients Median age (year, range) Gender (F/M) Duration (months) outcomes Jaded score
Black DM [20] PTH (1-84) 100 μg daily+ alendronate 10 mg daily 59 70.2 ± 6.8 F 12 Areal BMD: lumbar spine, total hip, femoral neck, distal radius. Volumetric BMD: lumbar spine, total hip, femoral neck, distal radius. Markers of bone turner 4
PTH (1-84) 100 μg daily 119 69.4 ± 7.3 F 12
Finkelstein JS [21] Teriparatide 40 μg subcutaneously daily+ alendronate 10 mg orally once daily 25 58 ± 8 M 30 Areal BMD: Posteroanterior spine, Lateral spine, total hip, femoral neck, distal radius, total body. 3
Teriparatide 40 μg sc daily 20 57 ± 9 M 30
Finkelstein JS [29] Teriparatide 40 μg sc daily+ alendronate 10 mg daily 20 62 ± 7 F 30 Areal BMD: Posterior-anterior spine, total hip, femoral neck, distal radius. Bone turner markers. 3
Teriparatide 40 μg sc daily 20 65 ± 7 F 30
Boonen S [30] Teriparatide 20 μg/d and daily supplements of 500 mg elemental calcium and 400-800 IU vitamin D + alendronate 107 70.3 F 24 Areal BMD: total hip, femoral neck, lumbar spine. 4
Teriparatide 20 μg/d and daily supplements of 500 mg elemental calcium and 400-800 IU vitaminD + non- bisphosphonate 49 67.9 F 24
Miller PD [31] Teriparatide 20 μg/d+ alendronate 10 mg daily or 70 mg weekly 146 67.7 ± 7.8 F 12 Areal BMD: total hip, femoral neck. Volumetric BMD: lumbar spine, total hip. Bone turner markers. 3
Teriparatide 20 μg/d 146 69.3 ± 7.4 F 12
Cosman F [32] Teriparatide 20 μg/d and daily supplements of 500 mg elemental calcium and 400-800 IU vitamin D + alendronate 52 67.8 ± 1.4 F 18 Areal BMD: lumbar spine, total hip, femoral neck. Biochemical markers of bone metabolism. 3
Teriparatide 20 μg/d and daily supplements of 500 mg elemental calcium and 400-800 IU vitamin D 50 69.1 ± 1.4 F 18