Table 1.

Characteristics of RCC patients and HDAC10 expression detected by immunohistochemistry and quantitative RT-PCR

Parameters	Total	HDAC10 mRNA	p		HDAC10	protein		p
				-	+	++	+++
RCC	145	2.69±0.24		45	66	23	11
Normal kidney	145	6.78±0.61	< 0.05	6	13	74	52	< 0.05
Gender
Male	85	2.70±0.21		25	41	13	6
Female	60	2.66±0.22	> 0.05	20	25	10	5	> 0.05
Age (years)
< 60	74	2.73±0.23		24	33	12	5
≥ 60	71	2.67±0.22	> 0.05	21	33	11	6	> 0.05
Tumor size
< 7 cm	81	3.56±0.32		21	32	19	9
≥ 7 cm	64	1.58±0.13	< 0.05	24	34	4	2	< 0.05
Histological grade
G1	65	3.71±0.32		14	28	14	9
G2	44	2.09±0.17		16	20	6	2
G3	36	1.58±0.13	< 0.05	15	18	3	0	< 0.05
Tumor stage
I	82	3.56±0.32		21	33	19	9
II	29	1.93±0.15		11	14	3	1
III	18	1.45±0.11		5	11	1	1
IV	16	0.96±0.08	< 0.05	8	8	0	0	< 0.05
Metastasis
M0	115	2.99±0.23		34	48	22	11
M1	30	1.34±0.11	< 0.05	11	18	1	0	< 0.05