Table 3.

Stratification analysis of genetic susceptibility of IFNG +874 T/A polymorphism to cancer risk

Category	A allele vs. T allele			AA vs. TT			AT vs. TT			AA+AT vs. TT			AA vs. AT+TT
	N	OR (95% CI)	P	N	OR (95% CI)	P	N	OR (95% CI)	P	N	OR (95% CI)	P	N	OR (95% CI)	P
Total	7	0.97 (0.73, 1.28)	<0.001	7	1.12 (0.68, 1.85)	<0.001	7	1.25 (0.97, 1.61)	0.263	7	1.19 (0.87, 1.63)	0.068	8	0.95 (0.64, 1.40)	<0.001
Ethnicity
Asian	3	1.11 (0.61, 2.02)	<0.001	3	1.43 (0.56, 3.65)	0.001	3	1.61 (1.14, 2.29)	0.963	3	1.56 (1.08, 2.24)	0.292	3	0.98 (0.35, 2.69)	<0.001
Caucasian	1	0.83 (0.73, 0.94)	-	1	0.71 (0.55, 0.91)	-	1	0.96 (0.76, 1.21)	-	1	0.85 (0.69, 1.06)	-	1	0.73 (0.60, 0.88)	-
African	1	0.73 (0.45, 1.17)	-	1	0.84 (0.26, 2.75)	-	1	1.36 (0.38, 4.74)	-	1	0.96 (0.30, 3.11)	-	1	0.65 (0.37, 1.13)c	-
Mixed	2	0.88 (0.66, 1.18)	0.330	2	1.02 (0.64, 1.62)	0.672	2	1.09 (0.37, 3.25)	0.218	2	1.20 (0.58, 2.06)	0.600	3	1.17 (0.62, 2.22)	0.021
Genotyping method
PCR-SSP	2	1.47 (1.11, 1.94)	0.939	2	2.14 (1.18, 3.86)	0.707	2	1.13 (0.36, 3.49)	0.194	2	1.63 (0.88, 3.03)	0.301	3	1.53 (1.16, 2.03)	0.672
TaqMan	1	0.83 (0.73, 0.94)	-	1	0.71 (0.55, 0.91)	-	1	0.96 (0.76, 1.21)	-	1	0.85 (0.69, 1.06)	-	1	0.73 (0.60, 0.88)	-
PCR-ARMS	4	0.87 (0.56, 1.37)	<0.001	4	1.05 (0.50, 2.17)	0.008	4	1.58 (1.11, 2.24)	0.983	4	1.19 (0.87, 1.85)	0.464	4	0.73 (0.36, 1.46)	<0.001
HWE status
Yes	6	1.05 (0.73, 1.53)	<0.001	6	1.20 (0.61, 2.34)	<0.001	6	1.26 (0.91, 1.76	0.136	6	1.23 (0.81, 1.87)	0.021	6	1.07 (0.64, 1.79)	<0.001
No	2	0.81 (0.62, 1.04)	0.615	2	1.11 (0.68, 1.85)	0.802	2	1.47 (0.78, 2.76)	0.881	2	1.19 (0.87, 1.63)	0.77	10	0.70 (0.51, 0.96)	0.768