Contributors to insulation in mice. A. Heat conductance after death. Mice were euthanized by cervical dislocation, Tb was monitored by E-mitter, and the mean heat conductance from 6 to 35 min after death was calculated for each mouse. To obtain a range of body weights, male and female chow-fed C57BL/6J, male and female Mc3r−/−;Mc4r−/− (DKO, raw data from Ref. [71]), and male high fat diet-fed C57BL/6J mice were studied, as indicated. B. Heat conductance summary. Heat conductance during life (Control and dashed reference line, from Figure 5D), after death (Dead, from A, using a body weight of 29 g), and of shaved (Shaved) and nude (Nude) living mice, both approximated based on data in Ref. [31]. The contribution of fur is the difference between the nude/shaved and control groups. The non-mechanical (“physiology’) component of insulation is the difference between the dead and nude/shaved groups.