Table 1. Most significant polymorphic positions (omnibus test) and imputed classical alleles associated with ankylosing spondylitis susceptibility (P-value<1 × 10−2000).
Position | rs | AA position | Classical allele | χ2 | DF | P-value |
---|---|---|---|---|---|---|
31,432,180 | — | 97 | — | 14,857 | 5 | <10−3,221 |
31,432,180 | rs1071652 | — | — | 14,841 | 3 | <10−3,221 |
31,430,829 | rs41558317 | — | — | 14,823 | 1 | <10−3,221 |
31,432,179 | rs1140412 | — | — | 14,823 | 2 | <10−3,219 |
— | — | — | HLA-B*27 | 14,820 | 1 | <10−3,221 |
31,432,506 | — | 70 | — | 14,812 | 3 | <10−3,215 |
31,432,129 | — | 114 | — | 14,402 | 2 | <10−3,128 |
31,432,130 | rs709055 | — | — | 14,401 | 2 | <10−3,128 |
31,432,131 | rs1050628 | — | — | 14,389 | 1 | <10−3,127 |
— | — | — | HLA-B*27:05 | 14,220 | 1 | <10−3,090 |
31,430,834 | rs3819282 | — | — | 13,798 | 1 | <10−2,999 |
31,430,345 | rs3819299 | — | — | 13,757 | 1 | <10−2,990 |
31,430,346 | rs3819299 | — | — | 13,757 | 1 | <10−2,990 |
31,451,646 | rs4463302 | — | — | 12,898 | 1 | <10−2,803 |
31,432,485 | — | 77 | — | 12,871 | 2 | <10−2,795 |
31,432,486 | rs1131217 | — | — | 12,849 | 1 | <10−2,793 |
31,377,108 | rs2394967 | — | — | 11,613 | 1 | <10−2,524 |
31,381,125 | rs6905036 | — | — | 11,552 | 1 | <10−2,511 |
31,432,208 | rs41556113 | — | — | 10,929 | 1 | <10−2,376 |
31,432,843 | rs41553720 | — | — | 10,299 | 2 | <10−2,237 |
31,432,515 | — | 67 | — | 9,741 | 4 | <10−2,112 |
31,432,515 | rs1071816 | — | — | 9,725 | 3 | <10−2,110 |
31,518,387 | rs2844510 | — | — | 9,525 | 1 | <10−2,071 |
AA, amino acid; DF, degrees of freedom.