Table 4.

Significant Gene–Environment interactions along with main effects

Gene	^Main effects	SNP ∗ environment	OR	Lower95ci	Upper95ci	p value †
TCF7L2	MG		0.512	0.36	0.728	0.0002
	VNV		0.604	0.391	0.932	0.023
	BMI		1.126	1.081	1.174	< 0.001
		TCF7L2 ∗ BMI	1.054	0.998	1.112	0.057
IGF2BP2	MG		0.347	0.221	0.546	< 0.001
	VNV		0.585	0.334	1.025	0.061
	Smoking		0.559	0.284	1.101	0.093
	BMI		1.114	1.058	1.173	< 0.001
		IGF2BP2 ∗ BMI	0.036	0.023	1.595	0.111
SLC30A8	BMI		1.15	1.056	1.251	0.001
CDKAL1	MG		0.577	0.409	0.814	0.002
	VNV		0.534	0.348	0.82	0.004
	BMI		1.14	1.094	1.188	< 0.001
		CDKAL1 ∗ MG	0.632	0.404	0.987	0.044
		CDKAL1 ∗ ALCOHOL	1.701	0.952	3.04	0.073
CDKN2A/B	MG		0.399	0.15	1.065	0.067
	VNV		0.321	0.098	1.05	0.06
HHEX	MG		0.42	0.276	0.639	< 0.001
	BMI		1.151	1.095	1.21	< 0.001
IRS-1	MG		0.429	0.326	0.565	< 0.001
	VNV		0.699	0.495	0.986	0.041
	BMI		1.15	1.11	1.18	< 0.0001
CAPN10	MG		0.445	0.326	0.607	< 0.001
	Smoking		0.601	0.377	0.956	0.031
	BMI		1.147	1.106	1.19	< 0.001
		CAPN10 ∗ smoking	4.954	0.928	26.442	0.061
PPARG	BMI		1.177	1.045	1.325	0.007

† 5% and 10% significance was considered.