Table 2.

Main results on association between interleukin-18 gene promoter (− 607C/A and − 137G/C) polymorphisms and chronic hepatitis C virus infections.

Contrast	OR, 95% CI	Heterogeneity	Z and P
IL-18 − 607C/A polymorphism
AA versus CC	1.073, [0.846, 1.360]	Chi-squared = 4.07 (d.f. = 3), p = 0.254, I-squared = 26.2%	z = 0.58, p = 0.563
AC versus CC	1.029, [0.854, 1.241]	Chi-squared = 2.33 (d.f. = 3), p = 0.506, I-squared = 0.0%	z = 0.30, p = 0.764
AA + AC versus CC	1.039, [0.872, 1.237]	Chi-squared = 3.21 (d.f. = 3), p = 0.361, I-squared = 6.5%	z = 0.42, p = 0.672
AA versus AC + CC	1.036, [0.843, 1.274]	Chi-squared = 3.16 (d.f. = 3), p = 0.368, I-squared = 5.0%	z = 0.34, p = 0.736
A versus C	1.029, [0.915, 1.158]	Chi-squared = 4.06 (d.f. = 3), p = 0.255, I-squared = 26.0%	z = 0.48, p = 0.634
IL-18 − 137G/C polymorphism
CC versus GG	1.257, [0.896,1.763]	Chi-squared = 0.74 (d.f. = 2), p = 0.690, I-squared = 0.0%	z = 1.32, p = 0.186
CG versus GG	1.200, [0.995,1.447]	Chi-squared = 0.00 (d.f. = 2), p = 0.998, I-squared = 0.0%	z = 1.91, p = 0.057
CG + CC versus GG	2.157, [1.822,2.553]	Chi-squared = 1.39 (d.f. = 2), p = 0.499, I-squared = 0.0%	z = 8.93, p = 0.000
CC versus CG + GG	2.007, [1.441,2.797]	Chi-squared = 0.57 (d.f. = 2) p = 0.751, I-squared = 0.0%	z = 4.12, p = 0.000
C versus G	1.152, [1.002,1.324]	Chi-squared = 0.27 (d.f. = 2) p = 0.874, I-squared = 0.0%	z = 1.99, p = 0.047