Table 3. Risk of cardiovascular events by categories of achieved apoB level.

On-trial apoB, mg/dL	<50	50-75	75-100	100-125	125-150	150-175	>175
Number of patients	1,278	10,085	12,989	9,769	2,969	824	239
Major cardiovascular events
Number	43	942	1,846	1,676	606	209	65
Event rate	3.4%	9.3%	14.2%	17.2%	20.4%	25.4%	27.2%
Unadjusted hazard ratio	0.21	0.41	0.51	0.61	0.72	0.94	1.00
95% confidence interval	(0.14-0.30)	(0.32-0.52)	(0.40-0.66)	(0.47-0.78)	(0.56-0.93)	(0.71-1.25)
Adjusted hazard ratio	0.59	0.55	0.59	0.64	0.71	0.91	1.00
95% confidence interval	(0.40-0.88)	(0.43-0.71)	(0.46-0.76)	(0.50-0.82)	(0.55-0.92)	(0.69-1.20)
Major coronary events
Number	30	723	1,573	1,483	531	186	57
Event rate	2.3%	7.2%	12.1%	15.2%	17.9%	22.6%	23.8%
Unadjusted hazard ratio	0.16	0.36	0.51	0.62	0.73	0.96	1.00
95% confidence interval	(0.11-0.25)	(0.27-0.47)	(0.39-0.66)	(0.47-0.80)	(0.55-0.96)	(0.71-1.29)
Adjusted hazard ratio	0.59	0.54	0.58	0.64	0.70	0.91	1.00
95% confidence interval	(0.37-0.93)	(0.41-0.70)	(0.45-0.76)	(0.49-0.83)	(0.53-0.92)	(0.68-1.22)
Major cerebrovascular events
Number	14	256	347	264	102	31	15
Event rate	1.1%	2.5%	2.7%	2.7%	3.4%	3.8%	6.3%
Unadjusted hazard ratio	0.34	0.52	0.44	0.43	0.53	0.60	1.00
95% confidence interval	(0.16-0.70)	(0.31-0.87)	(0.26-0.73)	(0.25-0.72)	(0.31-0.92)	(0.32-1.11)
Adjusted hazard ratio	0.45	0.49	0.51	0.52	0.61	0.61	1.00
95% confidence interval	(0.21-0.95)	(0.29-0.83)	(0.31-0.86)	(0.31-0.88)	(0.35-1.04)	(0.33-1.13)

Adjusted hazard ratios and corresponding 95% confidence intervals are adjusted for sex, age, smoking, diabetes mellitus, systolic blood pressure, HDL cholesterol, and trial. The highest apoB category was used as reference category. ApoB indicates apolipoprotein B.