Table 4.
HLA-DRB1 alleles and association with hAPLN
| HLA-DRB1 | All patients | LN | hAPLN | P value (after Bonferroni adjustment) | P value |
|---|---|---|---|---|---|
| (n = 110*) | (n = 94) | (n = 16) | |||
| *01 | 16 (15) | 16 (17) | 0 (0) | NS | 0.1 |
| *03 | 43 (39) | 36 (38) | 7 (44) | NS | 0.7 |
| *04 | 23 (21) | 20 (21) | 3 (19) | NS | NS |
| *07 | 12 (11) | 11 (12) | 1 (6) | NS | NS |
| *08 | 7 (6) | 6 (6) | 1 (6) | NS | NS |
| *09 | 4 (4) | 4 (4) | 0 (0) | NS | NS |
| *10 | 3 (3) | 2 (2) | 1 (6) | NS | 0.4 |
| *11 | 11 (10) | 11 (12) | 0 (0) | NS | 0.4 |
| *12 | 4 (4) | 4 (4) | 0 (0) | NS | NS |
| *13 | 28 (26) | 19 (20) | 9 (56) | 0.03 | 0.002 |
| *14 | 4 (4) | 3 (3) | 1 (6) | NS | 0.5 |
| *15 | 49 (45) | 44 (47) | 5 (31) | NS | 0.3 |
| *16 | 3 (3) | 2 (2) | 1 (6) | NS | 0.4 |
Values are shown as n (%). P values are comparisons between the two diagnostic groups: lupus nephritis (LN) and histopathological antiphospholipid-associated nephropathy (hAPLN). NS, not significant. *Genetic analysis had not been performed on two of the patients.