Skip to main content
. 2015 Mar 18;113(9):3345–3355. doi: 10.1152/jn.00973.2014

Table 3.

Summary of mouse TG cell types and previously reported properties in rats

Capsaicin Sensitivity
Previously Reported Properties
Type Cell Size Rm Em IB4 C57BL/6 BALB/c Rats CGRP SP Innervation
1 S High High ± ± ± ± + NR
2 S/M High High + ± * + H-skin
4 M Low Low H-skin
9 M Low High ± ± + + ± H-skin
13 M Low High + ± * + NR NR G-skin

For cell size, 11- to 22-μm and 23- to 34-μm cell diameter represent small (S) and medium (M), respectively. Findings for capsaicin sensitivity are relative to previous studies for rat TG neurons (Xu et al. 2010; Ono et al. 2010). The remaining properties are from previous studies on rat dorsal root ganglion (DRG) neurons (Petruska et al. 2000a,b, 2002; Rau et al. 2005, 2006, 2007, 2014; Jiang et al. 2006, 2013; Jiang and Cooper 2011).

IB4, isolectin B4; CGRP, calcitonin gene-related polypeptide; SP, substance P.

“+” And “−” indicate the presence and absence, respectively. NR indicates no report. H-skin and G-skin indicate hairy and glabrous skins, respectively. Note that there is a difference in capsaicin sensitivity in type 1 between Wister TG(±) and Sprague-Dawley DRG(+).

*

Difference for C57BL/6.

Difference for both mouse strains.