Table 5.

Associations between cancer variables and lifetime, 10-year and current multivitamin use among participants of the databank and biorepository at a comprehensive cancer centre in western New York, USA, December 2003–July 2012

	Lifetime				10 years				Current†
	Men		Women		Men		Women		Men		Women
	OR‡	95 % CI	OR‡	95 % CI	OR‡	95 % CI	OR‡	95 % CI	OR‡	95 % CI	OR‡	95 % CI
Cancer status§
Controls	1·00	Reference	1·00	Reference	1·00	Reference	1·00	Reference	1·00	Reference	1·00	Reference
Patients	0·87	0·71, 1·06	0·91	0·79, 1·04	0·86	0·70, 1·06	0·85	0·74, 0·99	0·78	0·64, 0·95	0·86	0·76, 0·97
Cancer type||
Benign	1·00	Reference	1·00	Reference	1·00	Reference	1·00	Reference	1·00	Reference	1·00	Reference
New	0·95	0·72, 1·25	0·79	0·64, 0·96	0·93	0·70, 1·23	0·81	0·65, 1·00	0·85	0·65, 1·12	0·79	0·66, 0·95
Recurrent	1·42	0·96, 2·12	0·80	0·54, 1·17	1·31	0·88, 1·97	0·70	0·47, 1·03	1·07	0·73, 1·56	0·80	0·56, 1·12
Cancer site||
Breast¶	1·32	0·44, 3·96	1·05	0·89, 1·23	2·18	0·60, 7·87	1·02	0·86, 1·20	1·30	0·46, 3·68	1·03	0·89, 1·19
Prostate¶	0·99	0·81, 1·19	N/A		1·00	0·82, 1·21	N/A		1·03	0·86, 1·24	N/A
Respiratory¶	1·03	0·78, 1·36	1·01	0·75, 1·35	0·96	0·72, 1·27	0·91	0·68, 1·23	1·08	0·82, 1·42	1·07	0·82, 1·40
Gastrointestinal¶	1·21	0·94, 1·56	0·81	0·61, 1·05	1·19	0·92, 1·54	0·89	0·67, 1·19	1·10	0·86, 1·40	0·78	0·60, 1·00
Gynaecological¶	N/A		0·91	0·76, 1·10	N/A		0·94	0·77, 1·14	N/A		1·07	0·90, 1·27
Genitourinary¶	0·96	0·75, 1·24	0·94	0·67, 1·33	0·96	0·74, 1·24	0·87	0·61, 1·24	0·94	0·73, 1·20	0·84	0·61, 1·15
Skin¶	0·91	0·62, 1·33	1·62	1·03, 2·55	0·99	0·67, 1·45	1·66	1·02, 2·70	0·87	0·60, 1·26	1·11	0·76, 1·62
Others††	0·86	0·66, 1·13	1·13	0·85, 1·50	0·87	0·66, 1·14	1·19	0·88, 1·61	0·90	0·69, 1·17	1·03	0·80, 1·33
Cancer stage‡‡
In situ	1·00	Reference	1·00	Reference	1·00	Reference	1·00	Reference	1·00	Reference	1·00	Reference
Localized	2·08	0·90, 4·82	0·83	0·59, 1·17	2·00	0·86, 4·61	0·97	0·69, 1·38	2·29	0·82, 5·66	0·87	0·65, 1·18
Regional	1·71	0·73, 4·00	0·70	0·49, 1·01	1·68	0·72, 3·93	0·89	0·62, 1·38	2·08	0·84, 5·20	0·76	0·55, 1·05
Distant	1·92	0·81, 4·55	0·73	0·49, 1·08	1·63	0·69, 3·85	0·94	0·63, 1·40	2·03	0·80, 5·11	0·63	0·44, 0·89
Unknown	2·49	1·04, 5·96	0·77	0·49, 1·20	1·99	0·83, 4·75	1·10	0·69, 1·74	2·36	0·93, 5·99	0·95	0·64, 1·42

N/A, not applicable.

^†Use at the time of enrolment into the databank and biorepository.

^‡Adjusted for age, race, education, family hx cancer, smoker status, BMI, total fruit and vegetable intake, physical activity.

^§Overall n 8096 (men=2787; women=5309).

^||Cancer patients only (overall=5418: men=2145; women=3273).

^¶Odds ratio compared with all other cancer sites or stages.

^††Odds ratio compared with all previously reported cancer sites.

^‡‡Cancer patients with malignancies (overall=4494: men=1890; women=2604).