Table 1.
First author (year) | Sample size (T/C) | Population characteristics | Intervention | Comparison | Duration of treatment | Outcome assessment | Conclusion |
---|---|---|---|---|---|---|---|
Liu, 2008 [37] | 120 (84/36) | Age: 21 to 60 (T/C: NA) Course: NA |
JG (4 g, Tid, PO) | Placebo (300 mg, Tid, PO) |
T: 28 days C: 28 days |
VAS (0 to 100) Diff: 18.53 |
The results suggested JG was better than placebo for reductions of pain in the treatment of CR. |
| |||||||
Jin, 2008 [38] | 120 (60/60) | Age: 27 to 59 (T/C: NA) Course: 3 hours to 5 days (T/C: NA) |
JG (4 g, Tid, PO) + C | First three days: 20% mannitol (250 mL, Ivgtt, Qd) + dexamethasone (10 mg, Ivgtt, Qd) After three days: 20% mannitol (250 mL, Ivgtt, Qd) + dexamethasone (5 mg, Ivgtt, Qd) |
T: 6 days C: 6 days |
VAS (0 to 10) Diff: 1.75 |
The result of randomized controlled clinical trial showed that both JG and western medicine therapies were effective and superior to single western medicine in relieving pain for CR. |
| |||||||
Liu, 2013 [39] | 160 (80/80) | Age: 26 to 66 (T: 26 to 66; C: 30 to 65) Course: 3 months to 5 years (T/C: 3 months to 5 years) |
JG (4 g, Qd, PO) + C | ICST (2 pills/time, Bid) |
T: 14 days (JC) C: 5 days |
VAS (0 to 10) Diff: 1.30 NDI Diff: 8.40 |
The improvements in VAS and NDI scores difference of intervention group were better than those of the control group. |
T: treatment group; C: control group; Diff: difference between before and after treatment in both groups; NA: not reported.
JG: Jingtong granule; ICST: ibuprofen codeine sustained tablets.
Tid: three times a day; Bid: twice a day; Qd: once a day; PO: oral administration; Ivgtt: intravenous guttae.
VAS: visual analogue scale; NDI: neck disability index; CR: cervical radiculopathy.