Table 3.

Changes in body weight gains in mice with NTX-induced muscle atrophy.

Groups	Body weights (g)			Body weight gains during the test article treatment period (g) [B − A]
	At NTX	At 14 days after NTX, first administration [A]	Sacrifice [B]
Controls
Sham	34.48 ± 1.12	32.80 ± 1.26	34.84 ± 1.27	2.04 ± 1.10
NTX	34.33 ± 0.98	32.00 ± 1.18	33.69 ± 1.62	1.69 ± 1.32
Reference
Oxymetholone	34.71 ± 1.42	32.47 ± 2.31	34.58 ± 3.22	2.11 ± 1.32
EESF treated
500 mg/kg	34.77 ± 1.59	32.82 ± 2.72	34.53 ± 2.75	1.71 ± 0.98
250 mg/kg	34.26 ± 1.41	32.65 ± 1.89	36.00 ± 3.31c	3.35 ± 1.89ab
125 mg/kg	34.47 ± 1.68	32.63 ± 2.03	34.40 ± 2.48	1.77 ± 1.19

Values are expressed as mean ± S.D. of 10 mice.

^a p < 0.05 as compared with sham control mice by the LSD test.

^b p < 0.01 and ^c p < 0.05 as compared with NTX control mice by the LSD test.