Table 2.
Cancers associated with paraneoplastic antibodies implicated in limbic encephalitis
| Antibody | Commonly associated tumors |
|---|---|
|
| |
| Against intracellular antigens | |
|
|
|
| Anti-Hu | Small cell lung cancer (SCLC) |
|
|
|
| Anti-Ma2 | Testicular germ-cell tumors, non-small cell lung cancer, breast cancer |
|
|
|
| Anti-CV2 | SCLC, thymoma |
|
|
|
| Anti-Ri | Neuroblastoma in children, breast and ovary cancer in adults |
|
|
|
| Anti-amphiphysin | SCLC, breast cancer |
|
|
|
| Anti-Zic4 | SCLC |
|
|
|
| Against cell membrane antigens | |
|
|
|
| Anti-VGKC | Thymoma, SCLC |
|
|
|
| Anti-NMDAR | Ovarian teratoma |
|
|
|
| Anti-AMPAR | Tumors of lung, breast, thymus |
|
|
|