. Author manuscript; available in PMC: 2016 Jun 1.

Published in final edited form as: Obstet Gynecol. 2015 Jun;125(6):1293–1298. doi: 10.1097/AOG.0000000000000853

Table 1.

Historical outbreaks of Ebola Virus Disease and Marburg Disease (Filovirus Infections) reporting pregnancy-related outcomes.

Where When (Reference)	Virus	Women infected n (% of total)	Pregnant women n (% of women)	Maternal outcome	Fetal/neonatal outcome
Zaire 1976 (30)	Ebola	177 (56%)	82 (46%)	89% mortality	19 SAb (23%, all 1^st/2^nd trim) 7/11 with fever at birth (64%) 11/11 babies died by DOL 19
Zaire 1995 (20)	Ebola	105 (33%)	15 (14%)	15/15 vaginal bleeding 14/15 died (93% mortality) 1/15 lived (had 3^rd trim SAb)	10/15 SAb (67%) 4/5 born in 3^rd trim died (80%) 1 live birth died on DOL 3
Republic of Congo (31)	Marburg	49 (32%)	3 (6%)	3/3 died (100% mortality)	2 SAb 1 live birth died on DOL 1
DRC 2014 (32)	Ebola	36 (52%)	1 (3%)	1/1 died (100% mortality)	1/1 SAb (100%)
Guinea 2014 (33)	Ebola	13 (35%)	None reported	No data	No data
Sierra Leone 2014 (17)	Ebola	59 (60%)	1 (1.7%)	Not reported 74% mortality overall	SAb prior to EVD diagnosis
Liberia 2014 (34)	Ebola	Not reported	4 reported (% not reported)	3/4 (75%) died after SAb in late 2^nd/3^rd trim	All resulted in SAb

SAb = spontaneous abortion, DOL = day of life, trim = trimester, DRC = Democratic Republic of the Congo (formerly Zaire), EVD = Ebola virus disease.

Outbreaks with no published data on pregnant are not included.