Table 5.

Results from risk optimization, describing which treatment plan confers the lowest predicted risk of second cancer following prostate radiotherapy. Results were obtained with normal tissue DVH constraints for linear and non-linear risk models. Axial slices of the treatment plans are shown in figure 1.

	With DVH Constraints
Risk model	Plan description	Gantry Angles (degrees)	Beam Weights	ERR bladder	ERR rectum	Plan Label
iirp (Shuryak et al)	Anterior and Lateral parallel-opposed	0, 90, 270	0.9, 0.05, 0.05	0.73	0.14	C
Linear-non-threshold	Lateral parallel-opposed	90, 270	0.5, 0.5	5.46	2.07	A
Linear-exponential-10	Anterior and Lateral parallel-opposed	0, 90, 270	0.9, 0.05, 0.05	0.32	0.09	C
Linear-exponential-40	Lateral parallel-opposed	90, 270	0.5, 0.5	1.54	0.59	A
Linear-plateau-10	Lateral parallel-opposed	90, 270	0.5, 0.5	0.74	0.27	A
Linear-plateau-40	Lateral parallel-opposed	90, 270	0.5, 0.5	1.74	0.65	A