Table 2.

Baseline ventilatory response to hypercapnia or hypoxia for WT and Pet1/DTR mice.

	VO2 (ml min−1 g−1)	VE (ml min−1 g−1)	VT (ml g−1)	fR (min−1)
Male WT
21% O2/5% CO2	0.049 ± 0.003	7.29 ± 0.62	0.024 ± 0.002	297 ± 9
21% O2/7% CO2	0.043 ± 0.002	10.10 ± 0.99	0.031 ± 0.003	325 ± 6
50% O2/7% CO2	0.034 ± 0.008	9.00 ± 1.02	0.029 ± 0.001	303 ± 9
10% O2/0% CO2	0.064 ± 0.007	3.79 ± 0.50	0.015 ± 0.001	248 ± 14
Female WT
21% O2/5% CO2	0.039 ± 0.003	7.05 ± 0.64	0.028 ± 0.002	248 ± 7
21% O2/7% CO2	0.034 ± 0.004	10.27 ± 0.48	0.035 ± 0.002	292 ± 5
50% O2/7% CO2	0.030 ± 0.006	9.56 ± 0.93	0.034 ± 0.003	280 ± 6
10% O2/0% CO2	0.058 ± 0.004	3.81 ± 0.56	0.017 ± 0.002	223 ± 12
Male Pet1/DTR
21% O2/5% CO2	0.049 ± 0.003	5.15 ± 0.47	0.019 ± 0.002	264 ± 6
21% O2/7% CO2	0.043 ± 0.003	6.69 ± 0.50	0.023 ± 0.002	291 ± 5
50% O2/7% CO2	0.045 ± 0.009	5.99 ± 0.46	0.022 ± 0.002	272 ± 5
10% O2/0% CO2	0.060 ± 0.006	2.90 ± 0.17	0.013 ± 0.001	225 ± 6
Female Pet1/DTR
21% O2/5% CO2	0.049 ± 0.002	7.12 ± 0.38	0.027 ± 0.001	265 ± 8
21% O2/7% CO2	0.044 ± 0.002	9.44 ± 0.56	0.032 ± 0.002	294 ± 9
50% O2/7% CO2	0.055 ± 0.010	8.53 ± 0.53	0.031 ± 0.001	274 ± 9
10% O2/0% CO2	0.056 ± 0.006	3.44 ± 0.23	0.016 ± 0.001	217 ± 7

Values are means ± SEM. VO₂, oxygen consumption; V_E, minute ventilation; V_T, tidal volume, and; f_R, respiratory frequency.