Figure 2.

UCX are less immunogenic than BM-MSCs. PBMCs from two different donors were incubated with a non-MSC cell line (Molt4), BM-MSC, and UCX from 3 independent donors. Lymphocyte proliferation was measured as [³H]thymidine uptake (ccpm). UCX, and to a lesser extent BM-MSC, failed to induce lymphocyte activation in an allogeneic MLR. Values are represented as mean ± s.e.m. and statistically significant differences are indicated by asterisks (one-way ANOVA with a Tukey posttest; ^∗ P < 0.05, ^∗∗ P < 0.01, and ^∗∗∗ P < 0.001).