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. Author manuscript; available in PMC: 2015 May 26.
Published in final edited form as: Biometrika. 2014 May 12;101(2):253–268. doi: 10.1093/biomet/asu009

Figure 2.

Figure 2

Estimates of the differential networks between ovarian cancer subtypes. The direct and fused graphical lasso estimators were thresholded and the separate estimator was further sparsified; see text. Black edges show increase in conditional dependency from ovarian cancer subtype C1 to subtypes C2–C6, gray edges show decrease. (a)–(c): KEGG 04350, TGF-β pathway, (d)–(f): KEGG 04210, Apoptosis pathway. (a)–(e) tuned using L∞ with (5), (f) tuned with λ1 = 0 and λ2 to give the same number of edges as (d); see text. Separate estimator not shown for apoptosis pathway.