Table 1. Sample Characteristics (n=872).
| Lifetime AUD | Current AUD | Past AUD | Unaffected 1st degree | Unaffected 2nd–5th degree | Unaffected unrelated controls | |
|---|---|---|---|---|---|---|
| Sample size | 297 | 188 | 109 | 137 | 211 | 227 |
| Female (%) | 36% | 39% | 29% | 77% | 76% | 69% |
| Left handed (%) | 9% | 10% | 9% | 4% | 6% | 7% |
| Age (years)a | 42.77 (13) | 45.13 (14) | 38.72 (13) | 52.6 (13) | 42.81 (15) | 40.22 (16) |
| Max drinksb | 17.15 (8) | 15.6 (8) | 19.78 (8) | 6.09 (7) | 6.93 (7) | 6.40 (6) |
| Age of first drink (years)a | 16.14 (4) | 16.37 (4) | 15.73 (3) | 21.55 (8) | 19.99 (6) | 19.88 (6) |
| Lifetime nicotine dependence | 59% | 59% | 59% | 23% | 20% | 18% |
| Current nicotine dependence | 41% | 35% | 52% | 12% | 15% | 14% |
| Lifetime substance abuse/dependence | 36% | 32% | 43% | 3% | 5% | 4% |
| Current substance abuse/dependence | 13% | 5% | 28% | 0% | 2% | 2% |
| Lifetime major depressive disorder | 40% | 40% | 40% | 42% | 23% | 27% |
| Current major depressive disorder | 11% | 9% | 15% | 12% | 5% | 10% |
| Recurrent major depressive disorder | 20% | 21% | 19% | 24% | 11% | 13% |
| Bipolar I disorder | 1% | 1% | 1% | 1% | 0% | 1% |
| Bipolar II disorder | 1% | 2% | 1% | 1% | 0% | 0% |
| Lifetime suicide attempt | 11% | 12% | 9% | 10% | 3% | 2% |
| Lifetime panic disorder | 10% | 10% | 11% | 10% | 7% | 8% |
| Current panic disorder | 7% | 6% | 7% | 4% | 4% | 4% |
| Lifetime social phobia | 2% | 2% | 3% | 3% | 4% | 4% |
| Current social phobia | 2% | 2% | 1% | 2% | 2% | 4% |
| Lifetime obsessive-compulsive disorder | 3% | 3% | 3% | 1% | 2% | 2% |
| Current obsessive-compulsive disorder | 3% | 3% | 2% | 1% | 1% | 1% |
| Generalized anxiety disorder | 5% | 4% | 7% | 1% | 1% | 1% |
| STAI statea.c | 33.15 (10) | 31 (10) | 35.59 (10) | 32.19 (9) | 30.97 (9) | 31.81 (10) |
| STAI traita,c | 36.91 (10) | 33.93 (9) | 40.18 (10) | 34.27 (7) | 32.65 (9) | 34.51 (10) |
| Beck Depression Inventory IIa,d | 9.05 (9) | 8.4 (8) | 10.15 (9) | 8.71 (8) | 6.66 (6) | 7.6 (9) |
a
Mean (SD).
b
Maximum lifetime drinks in 24 h, Mean (SD).
c
State-Trait Anxiety Inventory (STAI) (Spielberger et al, 1970).