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. 2014 Sep 17;40(2):502–512. doi: 10.1038/npp.2014.199

Figure 2.

Figure 2

Locomotor activity (OFT). Distance travelled in OFT, as a measure of baseline locomotor activity All data represent mean±SEM (n=10/group). Sal-aCSF: saline treatment IP with aCSF administered ICV, Sal-Etan: saline treatment IP with etanercept administered ICV, LPS-aCSF: LPS challenge IP with aCSF administered ICV, LPS-Etan: LPS challenge IP with etanercept administered ICV. Data compared using two-way ANOVA (Interaction: P=0.8254, Saline/LPS challenge: P<0.001, aCSF/etanercept treatment: P=0.25). **P<0.01 LPS-aCSF compared with Sal-aCSF-treated mice, analyzed by Bonferroni's multiple comparison.