Table 2. Proteins with cell adhesion and migration GO classification depleted from the cell surface upon A-769662 treatment.
Gene symbol | Protein description | Peptides detected in basal cond. | Peptides detected in A-769662 cond. | Peptides detected in background |
---|---|---|---|---|
FAT1 | FAT tumor suppressor 1 | 8 | 0 | 0 |
FAT2 | FAT tumor suppressor 2 | 6 | 0 | 0 |
FAT4 | FAT tumor suppressor 4 | 7 | 0 | 0 |
LYPD3 | LY6/PLAUR domain containing 3 | 7 | 0 | 0 |
NELL1 | PKC binding protein NELL1 | 5 | 0 | 0 |
NELL2 | PKC binding protein NELL2 | 4 | 0 | 0 |
SSPO | SCO-spondin | 7 | 0 | 0 |
CXCL12 | chemokine (C-X-C motif) ligand 12 | 4 | 0 | 0 |
COL6A3 | collagen, type VI, alpha 3 | 6 | 0 | 0 |
COL112 | collagen, type XI, alpha 2 | 4 | 0 | 0 |
COL14A1 | collagen, type XIV, alpha 1 | 6 | 0 | 0 |
DLG1 | discs, large homolog 1 | 5 | 0 | 0 |
FER | fer (fps/fes related) tyrosine kinase | 4 | 0 | 0 |
FERMT3 | fermitin family homolog 3 | 11 | 0 | 0 |
FNDC3A | fibronectin type III domain cont. 3A | 6 | 0 | 0 |
ITGA11 | integrin, alpha 11 | 14 | 0 | 0 |
ITGA4 | integrin, alpha 4 | 4 | 0 | 0 |
ICAM5 | intercellular adhesion molecule 5 | 5 | 0 | 0 |
LOXL2 | lysyl oxidase-like 2 | 5 | 0 | 0 |
MUC16 | mucin 16, cell surface associated | 15 | 0 | 0 |
MUC5AC | mucin 5AC, | 4 | 0 | 0 |
NRP1 | neuropilin 1 | 4 | 0 | 0 |
PKHD1 | polycystic kidney & hepatic disease 1 | 5 | 0 | 0 |
PCHD19 | protocadherin 19 | 5 | 0 | 0 |
PCHD19 | protocadherin 7 | 4 | 0 | 0 |
PCDHB10 | protocadherin β 9 | 4 | 0 | 0 |
PCDHGB3 | protocadherin gamma subfamily B, 3 | 6 | 0 | 0 |
SEMA5B | semaphorin 5A | 5 | 0 | 0 |
SDK1 | sidekick homolog 1 | 20 | 0 | 0 |
SORBS1 | sorbin and SH3 domain containing 1 | 15 | 0 | 0 |
SNED1 | sushi, nidogen & EGF-like domains 1 | 4 | 0 | 0 |
TRO | trophinin | 6 | 0 | 0 |
Shown are the 32 proteins with Cell Adhesion and Migration GO classification detected in the cell surface fraction of control but not A-769662 treated cells. Shown for each are the detected peptide counts in each of the treatment conditions.