Table 5. Accuracy of BD rapid influenza diagnostic tests (RIDTs) in different age groups.
BD Directigen Flu A+B test and BD Directigen EZ Flu A+B test | PCR negative | PCR positive | Prevalence % (95%CI) | Sensitivity % (95% CI) | Specificity % (95% CI) | PPV (%) | NPV (%) |
---|---|---|---|---|---|---|---|
<1 | |||||||
negative | 49 | 16 | 38(27–50) | 47(29–65) | 100(91–100) | 100(73–100) | 75(63–85) |
positive | 0 | 14 | |||||
n = 65 | |||||||
1–3 | |||||||
negative | 232 | 120 | 49(44–53) | 46(40–53) | 99(96–100) | 97(91–99) | 66(61–71) |
positive | 3 | 104 | |||||
n = 352 | |||||||
4–6 | |||||||
negative | 151 | 140 | 64(60–68) | 48(42–54) | 99(96–100) | 99(95–100) | 51(46–58) |
positive | 1 | 128 | |||||
n = 291 | |||||||
7–10 | |||||||
negative | 126 | 173 | 70(66–75) | 43(37–49) | 98(94–100) | 98(94–100) | 42(37–48) |
positive | 2 | 130 | |||||
n = 299 | |||||||
11–20 | |||||||
negative | 185 | 133 | 55(50–60) | 42(36–48) | 100(97–100) | 100(94–100) | 58(52–64) |
positive | 0 | 97 | |||||
n = 318 | |||||||
>20 | |||||||
negative | 174 | 134 | 48(43–54) | 18(12–25) | 99(94–99) | 97(81–100) | 57(51–62) |
positive | 1 | 29 | |||||
n = 308 | |||||||
Total | |||||||
negative | 917 | 716 | 57(55–59) | 41(38–44) | 99(98–100) | 98(97–99) | 56(54–59) |
positive | 7 | 502 | |||||
n = 1633 | 925 | 1218 |
Key: CI—confidence interval
PPV—positive predictive value
NPV—negative predictive value