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. 2015 May 26;10(5):e0127070. doi: 10.1371/journal.pone.0127070

Table 5. Accuracy of BD rapid influenza diagnostic tests (RIDTs) in different age groups.

BD Directigen Flu A+B test and BD Directigen EZ Flu A+B test PCR negative PCR positive Prevalence % (95%CI) Sensitivity % (95% CI) Specificity % (95% CI) PPV (%) NPV (%)
<1
negative 49 16 38(27–50) 47(29–65) 100(91–100) 100(73–100) 75(63–85)
positive 0 14
n = 65
1–3
negative 232 120 49(44–53) 46(40–53) 99(96–100) 97(91–99) 66(61–71)
positive 3 104
n = 352
4–6
negative 151 140 64(60–68) 48(42–54) 99(96–100) 99(95–100) 51(46–58)
positive 1 128
n = 291
7–10
negative 126 173 70(66–75) 43(37–49) 98(94–100) 98(94–100) 42(37–48)
positive 2 130
n = 299
11–20
negative 185 133 55(50–60) 42(36–48) 100(97–100) 100(94–100) 58(52–64)
positive 0 97
n = 318
>20
negative 174 134 48(43–54) 18(12–25) 99(94–99) 97(81–100) 57(51–62)
positive 1 29
n = 308
Total
negative 917 716 57(55–59) 41(38–44) 99(98–100) 98(97–99) 56(54–59)
positive 7 502
n = 1633 925 1218

Key: CI—confidence interval

PPV—positive predictive value

NPV—negative predictive value