Table 3. The pairwise correlation of UGT1As and UGT2B7 among metabolic activity reduction ratio, protein expression reduction ratio and mRNA expression reduction ratio.
Metabolism-Protein | Metabolism-mRNA | Protein-mRNA | |
---|---|---|---|
UGT1A | R 2 = 0.979 b , P<0.001 | R2 = 0.275 b , P = 0.321 | R2 = 0.264 b , P = 0.341 |
UGT1A1 | R 2 = 0.725 b ,P = 0.002 | R2 = 0.354 b , P = 0.196 | R2 = 0.218 b , P = 0.435 |
UGT1A4 | R 2 = 0.869 a , P<0.001 | R2 = 0.057 b , P = 0.840 | R2 = 0.257 b , P = 0.355 |
UGT1A9 | R 2 = 0.971 b ,P = 0.001 | R2 = 0.050 b , P = 0.860 | R2 = 0.164 b , P = 0.558 |
UGT2B7 | R 2 = 0.996 b ,P<0.001 | R2 = 0.164 b , P = 0.558 | R2 = 0.214 b , P = 0.443 |
aPearson Correlation
bSpearman's rho
Bold represents a significant difference.