Table 2. The effect of DBME on serum markers (ALAT, ASAT, ALP, bilirubin) in iron overloaded mice.
Treatment | ALAT (Unit/l) | % Change | ASAT (Unit/l) | % Change | ALP (Unit/l) | % Change | Bilirubin (mg/dl) | % Change |
---|---|---|---|---|---|---|---|---|
B | 15.25 ± 1.56 | - | 67.60 ± 5.78 | - | 33.08 ± 3.71 | - | 1.52 ± 0.09 | - |
C | 45.23 ± 2.45 c | 196.63 | 167.62 ± 4.64 c | 147.91 | 132.51 ± 6.42 c | 300.57 | 3.28 ± 0.20 c | 116.29 |
S50 | 38.38 ± 0.42 c e | 151.72 | 105.44 ± 2.98 c f | 55.95 | 107.88 ± 3.45 c f | 226.11 | 3.03 ± 0.65 b | 100.23 |
S100 | 28.43 ± 0.29 c f | 86.45 | 99.04 ± 3.30 c f | 46.48 | 64.89 ± 4.88 c f | 96.17 | 2.13 ± 0.24 b f | 40.27 |
S200 | 20.77 ± 0.48 c f | 36.19 | 81.09 ± 3.09 b f | 19.94 | 38.66 ± 3.72 b f | 16.86 | 1.77 ± 0.13 b f | 16.40 |
D | 23.29 ± 1.09 c f | 52.79 | 79.35 ± 4.36 a f | 17.36 | 61.01 ± 2.44 c f | 84.44 | 1.68 ± 0.15 f | 10.97 |
Values are mean ± SD of six observations.
a p<0.05
b p<0.01 and c p<0.001 significant difference from normal mice (B) group
e p<0.01 and f p<0.001significant difference from iron overloaded (C) group