Table 3. The effect of DBME on liver parameters (SOD, CAT, GST, GSH) in iron overloaded mice.
Treatment | SOD (Unit/mg protein) | % Change | CAT (Unit/mg protein) | % Change | GST (Unit/mg protein) | % Change | GSH (μg/mg protein | % Change |
---|---|---|---|---|---|---|---|---|
B | 0.55 ± 0.03 | - | 21.84 ± 3.12 | - | 5.76 ± 0.29 | - | 0.51 ± 0.02 | - |
C | 0.09 ± 0.04 c | 84.09 | 7.74 ± 2.5 c | 64.56 | 1.50 ± 0.3 c | 73.96 | 0.36 ± 0.01 c 3 | 28.40 |
S50 | 0.10 ± 0.05 c | 81.62 | 14.12 ± 2.73 c f | 35.35 | 2.50 ± 0.26 c d | 56.59 | 0.37 ± 0.01 c | 26.63 |
S100 | 0.29 ± 0.05 c f | 48.29 | 16.16 ± 2.68 c f | 26.01 | 3.25 ± 0.3 c e | 43.58 | 0.43 ± 0.03 b e | 14.79 |
S200 | 0.52 ± 0.05 f | 6.31 | 18.36 ± 2.29 c f | 15.93 | 3.86 ± 0.32 c f | 32.99 | 0.46 ± 0.02 c f | 8.87 |
D | 0.47 ± 0.05 a f | 15.31 | 16.14 ± 3.87 c f | 26.09 | 3.72 ± 0.36 c f | 35.42 | 0.48 ± 0.02 a f | 5.13 |
Values are mean ± SD of six observations.
a p<0.05, b p<0.01and c p<0.001 significant difference from normal mice (B) group
d p<0.05, e p<0.01 and f p<0.001 significant difference from iron overloaded (C) group