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. 2015 Mar 4;3(2):45–55. doi: 10.1002/iid3.42

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© 2015 The Authors. Immunity, Inflammation and Disease Published by John Wiley & Sons Ltd.

This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Expression of CD80 or CD86 on monocytes in culture after stimulation with LPS. The graphs present the percentage on CD80 or CD86 positive monocytes stimulated for 48 h with LPS in culture. Due to the high intra-group variability of monocyte phenotype, in order to assess the time related changes in monocyte surface expression of co-stimulatory molecule in laquinimod and placebo treated patients, the results were expressed as ± percentage change from baseline value for each individual patient.