Table 3. Microarray analysis showing 60 differentially expressed genes in spleen isolated from pigs fed with ZEA diet.

Gene symbol	Gene description	ZEA (Fc)	p-value	Regulation
	Cell signaling
AFAP1L2	actin filament associated protein 1-like 2	2.46	0.025	Up
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	2.01	0.005	Up
OR10J3	olfactory receptor, family 10, subfamily J, member 3	13.55	0.011	Up
NXPH3	neurexophilin 3	6.50	0.000	Up
RXRG	Retinoid X receptor, gamma	2.16	0.011	Up
TNNC2	troponin C type 2 (fast)	9.13	0.001	Up
PCSK6	proprotein convertase subtilisin/kexin type 6	2.66	0.019	Up
JAG1	jagged 1	2.43	0.000	Up
KRT8	keratin 8	2.16	0.032	Up
S100A12	S100 calcium binding protein A12	2.28	0.027	Up
TGFB2	transforming growth factor, beta 2	2.00	0.006	Up
PTGDR2	prostaglandin D2 receptor 2	2.14	0.032	Up
GPR128	G protein-coupled receptor 128	0.49	0.002	Down
CCRL1	chemokine (C-C motif) receptor-like 1	0.48	0.000	Down
OR6C68	olfactory receptor, family 6, subfamily C, member 68	0.34	0.006	Down
RXFP1	relaxin/insulin-like family peptide receptor 1	0.25	0.001	Down
OMG	oligodendrocyte myelin glycoprotein	0.43	0.014	Down
OMG	oligodendrocyte myelin glycoprotein	0.46	0.030	Down
LPL	lipoprotein lipase	0.43	0.004	Down
CA2	carbonic anhydrase II	0.42	0.018	Down
OMG	oligodendrocyte myelin glycoprotein	0.42	0.006	Down
	Cellular proliferation
PRG4	Proteoglycan 4	2.19	0.029	Up
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	2.38	0.042	Up
JAG1	jagged 1	2.43	0.000	Up
TGFB2	transforming growth factor, beta 2	2.00	0.006	Up
EPO	erythropoietin	0.35	0.004	Down
E2F1	E2F transcription factor 1	0.45	0.024	Down
FOXP3	forkhead box P3	0.31	0.029	Down
CD40LG	CD40 ligand	0.47	0.018	Down
	Cytokines
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	2.38	0.042	Up
TGFB2	transforming growth factor, beta 2	2.00	0.006	Up
AFAP1L2	actin filament associated protein 1-like 2	2.46	0.025	Up
PRG4	Proteoglycan 4	2.19	0.029	Up
CD40LG	CD40 ligand	0.47	0.018	Down
EPO	erythropoietin	0.35	0.004	Down
CD40LG	CD40 ligand	0.47	0.018	Down
TLR7	toll-like receptor 7	0.40	0.035	Down
	Inflammatory responses
SLC7A2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	3.03	0.004	Up
AFAP1L2	actin filament associated protein 1-like 2	2.46	0.025	Up
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	2.38	0.042	Up
SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	3.39	0.001	Up
CXCL2	chemokine (C-X-C motif) ligand 2	2.43	0.011	Up
S100A12	S100 calcium binding protein A12	2.28	0.027	Up
FOXP3	forkhead box P3	0.31	0.029	Down
CD40LG	CD40 ligand	0.47	0.018	Down
TLR7	toll-like receptor 7	0.40	0.035	Down
	Growth factors
AFAP1L2	actin filament associated protein 1-like 2	2.46	0.025	Up
PCSK6	proprotein convertase subtilisin/kexin type 6	2.66	0.019	Up
JAG1	jagged 1	2.43	0.000	Up
TGFB2	transforming growth factor, beta 2	2.00	0.006	Up
FOXP3	forkhead box P3	0.31	0.029	Down
	Transcription factors
ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	1.93	0.018	Up
MEOX2	mesenchyme homeobox 2	2.38	0.027	Up
MITF	microphthalmia-associated transcription factor	2.04	0.021	Up
ID2	inhibitor of DNA binding 2, dominant negative helix-loop-helix protein	1.95	0.003	Up
NFIX	Nuclear factor 1 X-type	2.14	0.009	Up
HDAC11	histone deacetylase 11	25.99	0.001	Up
E2F1	E2F transcription factor 1	0.45	0.025	Down
FOXP3	forkhead box P3	0.31	0.029	Down
RAB18	RAB18, member RAS oncogene family	0.49	0.023	Down