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. 2015 May 26;10(5):e0127512. doi: 10.1371/journal.pone.0127512

Fig 4. Relative mRNA expression of maternal factors in matured oocytes after Dnmt1 knockdown.

Fig 4

After siRNA injection into GV stage oocytes, the transcripts of maternal and apoptosis related genes in MII stage oocytes were examined, and Dnmt1 knockdown significantly reduced the transcripts of Gdf9, Bmp15, Zar1, Brg1, Mater, Hsf1, Oct4, Sod1 and Bcl2l1, but increased the expression of Bax. a-bValues for a given gene with different superscripts differed significantly (P<0.05).