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. 2015 May 26;10(5):e0127201. doi: 10.1371/journal.pone.0127201

Table 3. Predictors of GVL at baseline and at month 12 among participants receiving ART.

Variables adj. OR 95% CI P-value
Baseline model Plasma viral load 2.47 1.66, 3.67 < 0.0001
AIC = 183.62 (N = 96) Detectable IL-1β 1.68 1.32, 2.15 <0.0001
Age 1.04 0.99, 1.09 0.11
N. gonorrhoea at baseline. 4.6 1.26, 16.82 0.021
Month 12 model Genital viral load at baseline 0.62 (0.12, 3.27) 0.57
AIC 24.6 (N = 49) (Log10 RNA copies/mL)
IL-8 at baseline (Log10 pg/mL) 5.47 (0.61, 49.52) 0.13
Plasma Viral load at 12 month 2.3 (0.84, 6.3) 0.1
(Log10 RNA copies/mL)
MIP-1β at month 12 4.53 (0.96, 21.32) 0.06
(Log10 pg/mL)

Predictors of genital viral load ≥40 copies/mL at baseline and at month 12 were determined. Ninety six women initiating ART were included in the analysis at baseline. Forty-nine women receiving ART had viral load data available at month 12 and were included in the analysis at month 12. The variables included were:

At baseline: Plasma viral load, CD4, age, IL-8, IP-10, MIP-1b, VEGF, IL-6, GCSF, IL-1β, N. gonorrhoea, Chlamydia trachomatis, Trichomonas vaginalis, HSV2

At month 12: Use of family planning method, marital status, Trichomonas vaginalis at baseline & month 12, IL-8 at baseline & month 12, IP-10 at baseline & month 12, MIP-1b at month 12, IL-1β at month 12, IL-1RA at month 12, IL-6 at month 12, Genital VL at baseline, plasma VL at month 12.

AIC: Aikaike Information criteria.