Table 4.
Multiple linear regression modeling* results of leucocyte telomere length† (LTL) at visits 2 and 4 and change between visits 2 and 4‡ among the 356 Dental Atherosclerosis Risk in Communities participants.
| Leukocyte telomere length |
||||||
|---|---|---|---|---|---|---|
| Model: Visit 2 | Model 2: Visit 4 | Model 3: Change between visits 2 and 4 | ||||
| b (95% CI) | P | b (95% CI) | P | b (95% CI) | P | |
| Chronic periodontitis | ||||||
| None/mild | referent | referent | referent | |||
| Severe | −0.44 (−0.85, −0.04) | 0.03 | −0.43 (−0.83, −0.02) | 0.04 | 0.05 (−0.37, 0.47) | 0.8 |
| Number of teeth | −0.01 (−0.02, 0.01) | 0.5 | 0.01 (−0.01, 0.02) | 0.4 | 0.02 (−0.00, 0.32) | 0.08 |
| Sex | ||||||
| Female | referent | referent | referent | |||
| Male | −0.78 (−1.22, −0.34) | 0.001 | −0.62 (−1.05, −0.18) | 0.005 | 0.27 (−0.18, 0.72) | 0.2 |
| Race | ||||||
| African American | 0.27 (−0.23, 0.76) | 0.3 | 0.36 (−0.13, 0.85) | 0.1 | 0.12 (−0.39, 0.64) | 0.6 |
| White | referent | referent | referent | |||
| Smoking | −0.04 (−0.19, 0.11) | 0.6 | 0.01 (−0.14, 0.16) | 0.7 | 0.08 (−0.08, 0.23) | 0.3 |
| Age | −0.02 (−0.04, −0.00) | 0.1 | −0.02 (−0.04, −0.00) | 0.03 | −0.00 (−0.03, 0.02) | 0.7 |
| BMI category | 0.10 (−0.04, 0.25) | 0.2 | 0.06 (−0.09, 0.20) | 0.5 | −0.06 (−0.22, 0.09) | 0.4 |
| Income | ||||||
| < $12,000 | referent | referent | referent | |||
| $12,000 - $15,999 | −0.01 (−0.48, 0.45) | 0.9 | 0.01 (−0.44, 0.46) | 0.9 | 0.06 (−0.42, 0.54) | 0.8 |
| $16,000 - $24,999 | −0.30 (−0.72, 0.12) | 0.2 | −0.38 (−0.79, 0.03) | 0.07 | −0.08 (−0.51, 0.36) | 0.7 |
| $25,000 - $34,999 | 0.11 (−0.32, 0.54) | 0.6 | −0.08 (−0.50, 0.34) | 0.7 | −0.21 (−0.65, 0.23) | 0.3 |
| $35,000 - $49,999 | 0.39 (−0.07, 0.84) | 0.09 | 0.03 (−0.42, 0.47) | 0.9 | −0.44 (−0.91, 0.03) | 0.07 |
| $50,000 - $74,999 | 0.42 (−0.04, 0.87) | 0.07 | −0.02 (−0.46, 0.43) | 0.9 | −0.53 (−0.99, −0.06) | 0.03 |
| ≥ $75,000 | 0.51 (−0.02, 1.04) | 0.06 | 0.15 (−0.37, 0.67) | 0.6 | −0.43 (−0.98, 0.12) | 0.1 |
*
The multivariate linear regression models included terms for ARIC study examination center and a three-way interaction for the selection and matching variables (chronic periodontitis diagnosis*race*sex) the coefficients of which are suppressed in this table
†
LTL was measured using quantitative-polymerase chain reaction relative to a single-copy control gene, 36B4 (acidic ribosomal phosphoprotein P0)
‡
LTL and change scores were normalized via Z-score transformation prior to analysis