Skip to main content
. 2015 Apr 8;2(2):ENEURO.0001-15.2015. doi: 10.1523/ENEURO.0001-15.2015

Figure 1.

Figure 1

Comparison of AAV-GFP labeling of the mouse corticospinal tract. A, B, AAV8-CMV-GFP (B) labeled the dorsal CST slightly more efficiently than AAV2-CMV-GFP (A). C, However, AAV8-UbC-GFP labeled the dorsal tract and collaterals most efficiently compared with the other two viruses. DAPI-labeled nuclei are in blue. Insets show higher magnification of the dorsal CST and their collaterals. All images are from coronal tissue sections of mouse thoracic spinal cord 2 weeks postinjection. Scale bars: leftmost panels, 200 μm; all other panels, 100 μm. D, Comparison of number of axons labeled in the gray matter between different viruses. Axons quantified from specific regions of interest as detailed in Materials and Methods. Error bars represent SEM. n = 2 biological replicates per group.