Table 5. MMC Comparisons.
Characteristic | Total | MWRI | UCLA | t-test | Wilcoxon | Folded F |
---|---|---|---|---|---|---|
(N = 35) | (N = 17) | (N = 18) | p-value | p-value | test | |
(Mean ± SD) | (Variance) | |||||
Activation Panel | ||||||
Viability of CD3+ cells | 80.8 ± 15.6 | 77.0 ± 17.3 | 84.3 ± 13.4 | 0.143 | 0.040 | 0.276 |
CD4+ % of CD3+ cells | 62.2 ± 11.9 | 66.5 ± 11.5 | 58.1 ± 11.0 | 0.033 | 0.010 | 0.851 |
CD38+DR+ % of CD4+ cells | 9.2 ± 5.9 | 8.3 ± 4.5 | 10.1 ± 7.0 | 0.382 | 0.728 | 0.077 |
CD69+ % of CD4+ cells | 60.3 ± 15.7 | 68.3 ± 11.6 | 52.7 ± 15.5 | 0.002 | 0.002 | 0.248 |
CD8+ % of CD3+ cells | 30.4 ± 8.5 | 25.5 ± 6.6 | 35.0 ± 7.6 | <.001 | 0.001 | 0.563 |
CD38+DR+ % of CD8+ cells | 20.5 ± 10.0 | 16.4 ± 8.4 | 24.4 ± 10.0 | 0.015 | 0.023 | 0.466 |
CD69+ % of CD8+ cells | 70.5 ± 14.9 | 75.9 ± 11.9 | 65.5 ± 16.0 | 0.037 | 0.028 | 0.246 |
Memory Panel | ||||||
Viability of CD3+ cells | 79.6 ± 13.4 | 74.7 ± 20.2 | 84.3 ± 13.0 | 0.083 | 0.144 | 0.064 |
CD4+ % of CD3+ cells | 61.8 ± 11.6 | 67.4 ± 9.3 | 56.5 ± 11.3 | 0.004 | 0.002 | 0.442 |
CCR5+ % of CD4+ cells | 68.9 ± 14.7 | 65.6 ± 13.8 | 71.7 ± 15.2 | 0.233 | 0.173 | 0.703 |
CD27+CD45RA+% of CD4+ cells | 3.5 ± 6.1 | 1.6 ± 1.3 | 5.5 ± 8.3 | 0.079 | 0.814 | <.001 |
CD27+CD45RA- % of CD4+ cells | 20.3 ± 10.6 | 22.7 ± 12.0 | 17.8 ± 8.5 | 0.187 | 0.304 | 0.199 |
CD27-CD45RA+ % of CD4+ cells | 1.2 ± 1.6 | 0.6 ± 0.6 | 1.8 ± 2.1 | 0.038 | 0.026 | <.001 |
CD27-CD45RA- % of CD4+ cells | 75.0 ± 13.7 | 75.1 ± 11.9 | 74.9 ± 15.8 | 0.957 | 0.614 | 0.279 |
CD8+ % of CD3+ cells | 31.3 ± 8.7 | 26.9 ± 6.9 | 35.5 ± 8.3 | 0.002 | 0.004 | 0.473 |
CCR5+ % of CD8+ cells | 81.3 ± 13.0 | 81.3 ± 13.9 | 81.3 ± 12.5 | 0.992 | 1.000 | 0.678 |
CD27+CD45RA+ % of CD8+ cells | 3.7 ± 4.1 | 3.5 ± 3.4 | 4.0 ± 4.8 | 0.741 | 0.732 | 0.183 |
CD27+CD45RA- % of CD8+ cells | 17.7 ± 11.1 | 19.6 ± 12.7 | 15.7 ± 9.1 | 0.325 | 0.417 | 0.207 |
CD27-CD45RA % of CD8+ cells | 3.4 ± 6.5 | 2.2 ± 1.7 | 4.6 ± 9.1 | 0.314 | 0.652 | <.001 |
CD27-CD45RA- % of CD8+ cells | 75.2 ± 15.6 | 74.7 ± 15.6 | 75.7 ± 16.1 | 0.861 | 0.787 | 0.903 |