. 2015 May 26;10(5):e0127493. doi: 10.1371/journal.pone.0127493

Table 2. Cytotoxicity effects two nano-sized metal oxides on WAG cells after 24 h incubation as quantified with the MTT, NR and LDH assay.

Nanoparticle	Exposure Period and endpoint	IC₅₀(mg/L)	Hill slope	R² value	95% Confidence Interval
Nanoparticle	Exposure Period and endpoint	IC₅₀(mg/L)	Hill slope	R² value	IC₅₀ (mg/L)	Hill slope
TiO ₂	24 hour MTT assay	25.29±0.12	-1.59±0.06	0.958	21.27 to 31.18	-2.01 to -1.16
	24 hour Neutral Red uptake assay	34.99±0.09	-1.41±0.13	0.963	30.27 to 40.18	-1.84 to -1.07
	24 hour LDH assay	35.06±0.09	1.51±0.23	0.945	31.05 to 19.34	1.97 to 1.04
ZnO	24 hour MTT assay	5.716±0.1	-1.44±0.08	0.986	5.31 to 6.12	-1.89 to -1.11
	24 hour Neutral Red uptake assay	3.160±0.1	-1.33±0.1	0.964	2.68 to 3.51	-1.74 to -0.97
	24 hour LDH assay	5.57±0.12	1.392±0.11	0.952	5.16 to 6.08	1.83 to 0.98